À rebours (translated Against Nature or Against the Grain) is an 1884 novel by the French writer Joris-Karl Huysmans. The narrative centers on a single character: Jean des Esseintes, an eccentric, reclusive, ailing aesthete.

Charles-Marie-Georges Huysmans (5 February 1848 – 12 May 1907) was a French novelist and art critic who published his works as Joris-Karl Huysmans. He is most famous for the novel À rebours (1884, published in English as Against the Grain and as Against Nature). He supported himself by way of a 30-year career in the French civil service.