One in twenty-three people carry the genes for the synesthesia. Not a disorder but a neurological trait—like perfect pitch—synesthesia creates vividly felt cross-sensory couplings. A synesthete might hear a voice and at the same time see it as a color or shape, taste its distinctive flavor, or feel it as a physical touch.

Cytowic explains that synesthesia's most frequent manifestation is seeing days of the week as colored, followed by sensing letters, numerals, and punctuation marks in different hues even when printed in black. Other manifestations include tasting food in shapes, seeing music in moving colors, and mapping numbers and other sequences spatially. One synesthete declares, "Chocolate smells pink and sparkly"; another invents a dish (chicken, vanilla ice cream, and orange juice concentrate) that tastes intensely blue. Cytowic, who in the 1980s revived scientific interest in synesthesia, sees it now understood as a spectrum, an umbrella term that covers five clusters of outwardly felt couplings that can occur via several pathways. Yet synesthetic or not, each brain uniquely filters what it perceives. Cytowic reminds us that each individual's perspective on the world is thoroughly subjective.