Comprehensively updated with new information on bone marrow pathology – incorporating new advances in the diagnosis, classification and understanding of haematological disorders

This fifth edition has been extensively revised and expanded to reflect the significant advances that have occurred in the application of cytogenetics and, in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. It not only provides information on all common disease entities but also covers rare disorders in which bone marrow examination is useful. Designed as a practical resource for clinical use, it features 'Problems and Pitfalls' sections throughout to aid diagnosis.

Bone Marrow Pathology, 5th Edition is comprised of chapters covering: normal bone marrow; special techniques applicable to bone marrow diagnosis; infection and reactive changes; acute myeloid leukaemia, mixed phenotype acute leukaemia, myelodysplastic syndromes and histiocytic neoplasms; myeloproliferative and myelodysplastic/myeloproliferative neoplasms and related conditions; lymphoproliferative disorders; plasma cell neoplasms; disorders of erythropoiesis, granulopoiesis and thrombopoiesis; miscellaneous disorders; metastatic and non-haemopoietic tumours; and diseases of bone.

• Includes the recommendations of the 2016 WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues
• Summarizes key diagnostic techniques such as flow cytometric immunophenotyping, immunohistochemistry and cytogenetic and molecular genetic analysis
• Features new diagnostic algorithms and summary boxes
• Contains 600 colour illustrations including high-quality digital photomicrographs
• Offers specific information for clinicians working in low- and middle-income countries

Practical and highly applicable, Bone Marrow Pathology, 5th Edition is an essential resource for haematologists, haemato-oncologists, haematopathologists and pathologists, plus trainees and laboratory scientists in these disciplines.

Bone Marrow Pathology has been extensively revised to reflect the significant advances which have occurred in the application of cytogenetics and in particular, molecular genetics in the diagnosis, classification and understanding of haematological disorders. This comprehensive book not only provides information on all common disease entities, but also covers rare disorders in which bone marrow examination is useful. It is designed as a practical resource with "problems and pitfalls" highlighted throughout to aid laboratory diagnosis.