The purpose of the book entitled The Science of Sciences and The Science in Sciences is to show the origin of the Modern Scientific and Mathematical methods in Ancient and Traditional African culture and philosophy; To describe the method by which information is acquired, processed and used; To establish a complete Philosophy of Science ; and To teach the Science of God used for Creating Creations. This book is an introductory educational tool for a long term goal and mission of growing, cultivating, nurturing, and promoting African Creativity, and Ingenuity to develop, engineer, innovate, invent, and create any structures, devices, or systems needed. The importance of Science is emphasized in this book to motivate the reader to embrace Ancient and Traditional African scientific-based culture and philosophy to become creators of advanced operative Sciences and Technologies for survival, well being, problem solving, liberation, healing, and positive standards of living and higher quality of life.