The story of one man's evolution from naïve and ambitious young intern to world-class neurosurgeon.

With poignant insight and humor, Frank Vertosick Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick’s patients and unsparing yet fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain—the culmination of decades spent struggling to learn an unforgiving craft—illuminates both the mysteries of the mind and the realities of the operating room.