This text provides an overview of methods for epidemiological and clinical research on neurological disorders. The focus is on classic principles of study design in epidemiological research, strategies for avoiding study biases, methods for conducting clinical trials and prognostic studies, and principles of evidence-based medicine in neurology.



Neuroepidemiology is the epidemiologic study of neurological conditions. This text provides a comprehensive and accessible overview of research methods for conducting epidemiologic and clinical research on these conditions. It is aimed at neurologists, epidemiologists and public health professionals, as well as students of these disciplines. The book has three parts, each emphasizing the unique aspects of studying neurologic disorders. The first focuses on classic principles of epidemiologic and clinical research, including study design, sources of study bias, and methods for assessing the role of environmental and genetic factors in neurologic disorders. The second part covers each of the major neurologic disorders, with an emphasis of the methodologic aspects of studying these disorders and discussion of future research directions. The third part is devoted to clinical and translational research methods, including the design and conduct of clinical trials and prognostic studies, as well as the principles of health services research and evidence-based medicine.